Develops therapeutic products and diagnostic devices for diseases where aggregated misfolded proteins (AMP) are prevalent. These include transmissible spongiform encephalopathies (TSE), such as bovine spongiform encephalopathy (BSE) and the human form variant Creutzfeldt-Jakob Disease (vCJD), as well as neurodegenerative diseases such as Alzheimer's disease (AD) and amyotrophic lateral sclerosis (ALS), and cancer.